Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 19/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19891974 | 0.78 | BTK (0.44) | BTKBRD4LCK | |
| SCHEMBL24426204 | 0.77 | BTK (0.45) | BTKBRD4LCK | |
| SCHEMBL19876220 | 0.76 | BTK (0.57) | BTKLCK | |
| SCHEMBL24426199 | 0.76 | BTK (0.42) | BTKBRD4LCK | |
| SCHEMBL19876222 | 0.71 | BTK (0.43) | BTKBRD4 | |
| SCHEMBL24426168 | 0.68 | BTK (0.51) | BTKLCK | |
| SCHEMBL19876179 | 0.66 | BTK (0.82) | BTKLCK | |
| SCHEMBL19876207 | 0.66 | BTK (0.60) | BTKLCK | |
| SCHEMBL19876216 | 0.65 | BTK (0.57) | BTKBRD4 | |
| Hydrochloric Acid SCHEMBL19876241 | 0.65 | BTK (0.56) | BTKBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3500569-B1 | 2-OXO-IMIDAZOPYRIDINES AS REVERSIBLE BTK INHIBITORS AND USES THEREOF | MERCK PATENT GMBH (DE) | 2022-05-18 | — | — | EP | disclosed |