SCHEMBL24426488

SCHEMBL24426488

CC#Cc1cc(C)c(C2C(=O)CC3(CCN(C(=O)NC=O)CC3)CC2=O)c(C)c1

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22992095 0.89 PIK3CA (0.34) HIF1A
SCHEMBL22992125 0.87 CYP2D6 (0.33) HIF1A
SCHEMBL21344248 0.87 HIF1A (0.32) HIF1A
SCHEMBL21343678 0.86 CSNK1D (0.33) HIF1A
SCHEMBL22992121 0.86 KMT2A (0.36) HIF1A
SCHEMBL21343729 0.86 CYP3A4 (0.42) HIF1A
SCHEMBL22992166 0.86 EPHX2 (0.36)
SCHEMBL21344858 0.85 MEN1 (0.32)
SCHEMBL22992145 0.85 GAA (0.33)
SCHEMBL21274089 0.85 BTK (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3762378-B1 HERBICIDAL COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2022-05-18 EP disclosed