Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 6/20 | 0.54 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | F11 | P03951 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23486492 | 0.81 | NOTUM (0.54) | NOTUMF2ALDH1A1KMT2AKDM4E | |
| SCHEMBL14873776 | 0.81 | NOTUM (0.54) | NOTUMF2ALDH1A1KMT2AKDM4E | |
| SCHEMBL23088219 | 0.78 | NOTUM (0.51) | NOTUMF2ALDH1A1KMT2AKDM4E | |
| SCHEMBL23088294 | 0.78 | NOTUM (0.51) | NOTUMF2ALDH1A1KMT2AKDM4E | |
| SCHEMBL29792599 | 0.78 | NOTUM (0.51) | NOTUMF2ALDH1A1KMT2AKDM4E | |
| SCHEMBL23747894 | 0.77 | NOTUM (0.50) | NOTUMF2ALDH1A1KMT2ANPSR1 | |
| SCHEMBL15562531 | 0.77 | NOTUM (0.50) | NOTUMF2ALDH1A1NPSR1POLB | |
| SCHEMBL14873801 | 0.77 | NOTUM (0.50) | NOTUMF2ALDH1A1KMT2AKDM4E | |
| SCHEMBL16132838 | 0.77 | NOTUM (0.50) | NOTUMF2ALDH1A1KMT2AKDM4E | |
| SCHEMBL23747880 | 0.77 | NOTUM (0.50) | NOTUMF2ALDH1A1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3998263-A1 | TRICYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | Shanghai Jemincare Pharmaceuticals Co., Ltd. (CN) | 2022-05-18 | — | — | EP | disclosed |