Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EHMT2 | Q96KQ7 | 17/20 | 1.00 |
| ▸ | SPIN1 | Q9Y657 | 9/20 | 0.77 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17106569 | 1.00 | EHMT2 (1.00) | EHMT2SPIN1EHMT1 | |
| SCHEMBL17106573 | 1.00 | EHMT2 (1.00) | EHMT2SPIN1EHMT1 | |
| SCHEMBL17106566 | 0.93 | EHMT2 (1.00) | EHMT2SPIN1EHMT1 | |
| SCHEMBL25609625 | 0.91 | EHMT2 (0.83) | EHMT2SPIN1EHMT1 | |
| SCHEMBL25609623 | 0.91 | EHMT2 (0.83) | EHMT2SPIN1EHMT1 | |
| SCHEMBL20028668 | 0.90 | EHMT2 (0.81) | EHMT2SPIN1EHMT1 | |
| SCHEMBL20028664 | 0.90 | EHMT2 (0.81) | EHMT2SPIN1EHMT1 | |
| SCHEMBL20028345 | 0.87 | EHMT2 (1.00) | EHMT2SPIN1EHMT1 | |
| SCHEMBL30051800 | 0.87 | EHMT2 (1.00) | EHMT2SPIN1EHMT1 | |
| SCHEMBL20028041 | 0.87 | EHMT2 (0.96) | EHMT2SPIN1EHMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3519393-B1 | SUBSTITUTED FUSED BI- OR TRI- HETEROCYCLIC COMPOUNDS AS EHMT2 INHIBITORS | EPIZYME INC (US) | 2022-05-18 | — | — | EP | disclosed |