SCHEMBL24429081

SCHEMBL24429081

Cc1cc(Oc2nc(O)c3ccncc3n2)ccc1N(C)c1ccc(C2CCNCC2)cc1

nearest known ligand 0.47

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ KDM4C Q9H3R0 20/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17898276 0.90 KDM4C (0.58) KDM4C
SCHEMBL17898270 0.89 KDM4C (0.45) KDM4C
SCHEMBL17898306 0.87 KDM4C (0.46) KDM4C
SCHEMBL17602230 0.83 KDM4C (0.63) KDM4C
SCHEMBL17898281 0.82 KDM4C (0.54) KDM4C
SCHEMBL17615785 0.82 KDM4C (0.66) KDM4C
SCHEMBL17891451 0.82 KDM4C (0.66) KDM4C
SCHEMBL17891454 0.82 KDM4C (0.57) KDM4C
SCHEMBL17615558 0.81 KDM4C (0.49) KDM4C
SCHEMBL17898297 0.81 KDM4C (0.39) KDM4C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3430008-B1 HISTONE DEMETHYLASE INHIBITORS CELGENE QUANTICEL RES INC (US) 2022-05-18 — — EP disclosed
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