SCHEMBL24429168

SCHEMBL24429168

C=C/C(=C\C=C(/C)C(C)C)N(c1ccc(Oc2nc(O)c3ccncc3n2)cc1C)C1CCCN(C)C1

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ KDM4C Q9H3R0 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17898285 0.81 KDM4C (0.36) KDM4C
SCHEMBL17898266 0.79 KDM4C (0.46) KDM4C
SCHEMBL17898292 0.77 KDM4C (0.41) KDM4C
SCHEMBL17898265 0.74 KDM4C (0.46) KDM4C
SCHEMBL17898279 0.73 KDM4C (0.39) KDM4C
SCHEMBL17898295 0.73 KDM4C (0.45) KDM4C
SCHEMBL17891470 0.73 KDM4C (0.54) KDM4C
SCHEMBL17898303 0.73 KDM4C (0.40) KDM4C
SCHEMBL17898308 0.72 KDM4C (0.44) KDM4C
SCHEMBL17898264 0.71 KDM4C (0.47) KDM4C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3430008-B1 HISTONE DEMETHYLASE INHIBITORS CELGENE QUANTICEL RES INC (US) 2022-05-18 — — EP disclosed
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