Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 19/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | HCRTR2 | O43614 | 13/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2443213 | 1.00 | HCRTR1 (0.44) | HCRTR1KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL2446845 | 0.89 | HCRTR1 (0.55) | HCRTR1HCRTR2 | |
| SCHEMBL2446849 | 0.89 | HCRTR1 (0.55) | HCRTR1HCRTR2 | |
| SCHEMBL2442511 | 0.89 | HCRTR1 (0.47) | HCRTR1HCRTR2 | |
| SCHEMBL2442508 | 0.89 | HCRTR1 (0.47) | HCRTR1HCRTR2 | |
| SCHEMBL2443221 | 0.85 | HCRTR1 (0.50) | HCRTR1KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL2444513 | 0.84 | KDM4E (0.45) | HCRTR1KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL2444515 | 0.84 | KDM4E (0.45) | HCRTR1KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL2450796 | 0.81 | HCRTR1 (0.51) | HCRTR1HCRTR2 | |
| SCHEMBL2450794 | 0.81 | HCRTR1 (0.51) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2164847-B1 | 3-AZA-BICYCLO[3.3.0]OCTANE COMPOUNDS | ACTELION PHARMACEUTICALS LTD (CH) | 2011-09-14 | — | — | EP | claimed |