SCHEMBL24433112

SCHEMBL24433112

c1cncc(-c2c3ccccc3c(-c3ccc(-c4nc5ccccc5nc4-c4ccc5c(c4)C4(c6ccccc6-c6ccccc64)c4ccccc4-5)cc3)c3ccccc23)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 4/20 0.44
CYP11B1 P15538 2/20 0.41
DHODH Q02127 1/20 0.38
KDM4E B2RXH2 1/20 0.36
ALDH1A1 P00352 1/20 0.36
GAA P10253 1/20 0.36
MAPT P10636 1/20 0.36
CYP2A6 P11509 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP19A1 P11511 2/20 0.35
CYP17A1 P05093 1/20 0.35
CYP11B2 P19099 1/20 0.35
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
RAD51 Q06609 1/20 0.34
F2 P00734 1/20 0.34
HPGD P15428 1/20 0.34
TGFBR1 P36897 1/20 0.34
L3MBTL1 Q9Y468 2/20 0.34
MAPK10 P53779 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24433122 0.96 PDK2 (0.44) PDK2CYP11B1DHODHKDM4EALDH1A1
SCHEMBL24433148 0.94 PDK2 (0.47) PDK2CYP11B1DHODHKDM4EALDH1A1
SCHEMBL13726657 0.90 PDK2 (0.51) PDK2CYP11B1DHODHKDM4EALDH1A1
SCHEMBL13726541 0.89 PDK2 (0.53) PDK2CYP11B1DHODHKDM4EALDH1A1
SCHEMBL13728260 0.88 PDK2 (0.55) PDK2CYP11B1DHODHALDH1A1CYP2A6
SCHEMBL13726054 0.87 PDK2 (0.52) PDK2CYP11B1DHODHKDM4EALDH1A1
SCHEMBL13726910 0.87 PDK2 (0.54) PDK2CYP11B1DHODHKDM4EALDH1A1
SCHEMBL13727937 0.87 PDK2 (0.54) PDK2CYP11B1DHODHALDH1A1CYP2A6
SCHEMBL13726813 0.86 PDK2 (0.53) PDK2CYP11B1DHODHKDM4EALDH1A1
SCHEMBL24433149 0.85 PDK2 (0.42) PDK2CYP11B1DHODHKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220158100-A1 Organic Compound, Light-Emitting Device, Light-Emitting Apparatus, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2022-05-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220158100-A1 Organic Compound, Light-Emitting Device, Light-Emitting Apparatus, Electronic Device, and Lighting Device NQO1, CYP1A1, CYBA PDK2 737/4885CYP11B1 585/4885DHODH 489/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.