SCHEMBL24434320

SCHEMBL24434320

C=C(C)C(=O)OCCOC(=O)Nc1cccc(SC)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.52
KMT2A Q03164 3/20 0.52
SMN1; SMN2 Q16637 5/20 0.50
MAPT P10636 4/20 0.50
POLB P06746 2/20 0.50
CYP1A2 P05177 2/20 0.50
CYP3A4 P08684 2/20 0.50
TP53 P04637 1/20 0.50
MAPK1 P28482 1/20 0.50
HSD17B10 Q99714 1/20 0.50
HPGD P15428 4/20 0.49
ALDH1A1 P00352 2/20 0.48
GAA P10253 1/20 0.48
RAB9A P51151 3/20 0.47
LMNA P02545 2/20 0.47
NPC1 O15118 2/20 0.47
CYP2D6 P10635 1/20 0.47
CYP2C9 P11712 1/20 0.47
CYP2C19 P33261 1/20 0.47
GRM4 Q14833 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3204560 0.96 MEN1 (0.49) MEN1KMT2ASMN1; SMN2MAPTPOLB
SCHEMBL29638347 0.86 MEN1 (0.48) MEN1KMT2ASMN1; SMN2MAPTPOLB
SCHEMBL23391666 0.86 MEN1 (0.48) MEN1KMT2ASMN1; SMN2MAPTPOLB
SCHEMBL21695751 0.84 MEN1 (0.57) MEN1KMT2ASMN1; SMN2MAPTPOLB
SCHEMBL172243 0.82 MEN1 (0.52) MEN1KMT2ASMN1; SMN2MAPTPOLB
SCHEMBL29410992 0.82 MEN1 (0.52) MEN1KMT2ASMN1; SMN2MAPTPOLB
SCHEMBL2034715 0.82 HPGD (0.51) MEN1KMT2ASMN1; SMN2MAPTPOLB
SCHEMBL126634 0.81 SMN1; SMN2 (0.53) MEN1KMT2ASMN1; SMN2MAPTPOLB
SCHEMBL16145901 0.81 MEN1 (0.60) MEN1KMT2ASMN1; SMN2MAPTPOLB
SCHEMBL1087332 0.81 NPC1 (0.60) MEN1KMT2ASMN1; SMN2TP53HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022104113-A1 SUBSTITUTED MONO- AND POLY-PHENYL-CORE MONOMERS AND POLYMERS THEREOF FOR VOLUME BRAGG GRATINGS FACEBOOK TECHNOLOGIES, LLC (US) 2022-05-19 WO disclosed
US-20220153693-A1 SUBSTITUTED MONO- AND POLY-PHENYL-CORE MONOMERS AND POLYMERS THEREOF FOR VOLUME BRAGG GRATINGS META PLATFORMS TECHNOLOGIES, LLC 2022-05-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220153693-A1 SUBSTITUTED MONO- AND POLY-PHENYL-CORE MONOMERS AND POLYMERS THEREOF FOR VOLUME BRAGG GRATINGS PARG, PARN, PCBP1 MEN1 907/4885KMT2A 200/4885SMN1; SMN2 3172/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.