Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22006483 | 1.00 | LRRK2 (0.63) | LRRK2CYP1A2 | |
| SCHEMBL22006028 | 0.90 | LRRK2 (0.66) | LRRK2 | |
| SCHEMBL24435695 | 0.90 | LRRK2 (0.66) | LRRK2 | |
| SCHEMBL22006135 | 0.89 | LRRK2 (0.58) | LRRK2CYP1A2 | |
| SCHEMBL24435734 | 0.89 | LRRK2 (0.58) | LRRK2CYP1A2 | |
| SCHEMBL22006484 | 0.89 | LRRK2 (0.58) | LRRK2CYP1A2 | |
| SCHEMBL22006131 | 0.89 | LRRK2 (0.58) | LRRK2CYP1A2 | |
| SCHEMBL24435717 | 0.87 | LRRK2 (0.67) | LRRK2CYP1A2 | |
| SCHEMBL24435751 | 0.87 | LRRK2 (0.67) | LRRK2CYP1A2 | |
| SCHEMBL24400072 | 0.85 | LRRK2 (0.67) | LRRK2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220153728-A1 | COMPOUNDS, COMPOSITIONS AND METHODS | DENALI THERAPEUTICS INC. (US) | 2022-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220153728-A1 | COMPOUNDS, COMPOSITIONS AND METHODS | LRRK2, SNCA, GSK3B | LRRK2 1/4885CYP1A2 4556/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.