SCHEMBL24436697

SCHEMBL24436697

CC(=O)Oc1cc(F)cc(O)c1F

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 2/20 0.42
CYP4A11 Q02928 2/20 0.42
TNFSF11 O14788 1/20 0.39
PIM1 P11309 1/20 0.39
KDM4E B2RXH2 5/20 0.38
ALDH1A1 P00352 3/20 0.38
TSHR P16473 3/20 0.38
GAA P10253 2/20 0.38
RAB9A P51151 1/20 0.38
CFD P00746 2/20 0.37
HSD17B10 Q99714 3/20 0.36
HPGD P15428 2/20 0.36
USP2 O75604 1/20 0.36
CYP2C19 P33261 1/20 0.36
CYP3A4 P08684 1/20 0.35
ESR1 P03372 1/20 0.35
ITGB3 P05106 1/20 0.35
ITGA2B P08514 1/20 0.35
HMGB1 P09429 1/20 0.35
GGT1 P19440 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1998350 0.82 CYP4F2 (0.46) CYP4F2CYP4A11TNFSF11KDM4EALDH1A1
SCHEMBL24445897 0.82 CYP4F2 (0.42) CYP4F2CYP4A11TNFSF11PIM1KDM4E
SCHEMBL24436690 0.77 PIM1 (0.46) CYP4F2CYP4A11TNFSF11PIM1KDM4E
SCHEMBL24436813 0.77 ERN1 (0.46) CYP4F2CYP4A11TNFSF11PIM1KDM4E
SCHEMBL17374933 0.77 PIM1 (0.46) CYP4F2CYP4A11PIM1KDM4EALDH1A1
SCHEMBL18341964 0.76 CYP4F2 (0.44) CYP4F2CYP4A11TNFSF11KDM4EALDH1A1
SCHEMBL24445888 0.75 MAOB (0.40) KDM4EALDH1A1TSHRRAB9AHSD17B10
SCHEMBL24436812 0.73 CYP4F2 (0.45) CYP4F2CYP4A11TNFSF11PIM1KDM4E
SCHEMBL6194083 0.73 MAPK1 (0.47) CYP4F2CYP4A11PIM1KDM4EALDH1A1
SCHEMBL24436820 0.73 CYP4F2 (0.45) CYP4F2CYP4A11TNFSF11PIM1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4001336-A1 POLYURETHANE, POLYURETHANE PRODUCTION METHOD, CONDUCTIVE PASTE COMPOSITION, CONDUCTIVE WIRE, AND METHOD FOR PRODUCING CONDUCTIVE WIRE Shin-Etsu Chemical Co., Ltd. (JP) 2022-05-25 EP disclosed
US-20220157484-A1 POLYURETHANE, POLYURETHANE PRODUCTION METHOD, CONDUCTIVE PASTE COMPOSITION, CONDUCTIVE WIRE, AND METHOD FOR PRODUCING CONDUCTIVE WIRE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2022-05-19 US disclosed