Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 5/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 5/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.34 |
| ▸ | FABP4 | P15090 | 2/20 | 0.33 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.33 |
| ▸ | KMO | O15229 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29672232 | 0.84 | FFAR4 (0.39) | FFAR4PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL29672278 | 0.82 | CSNK2A1 (0.36) | FFAR4APPPDE4APDE4DPDE4B | |
| SCHEMBL24439721 | 0.82 | CSNK2A1 (0.36) | FFAR4APPPDE4APDE4DPDE4B | |
| SCHEMBL24439481 | 0.81 | FFAR4 (0.38) | FFAR4PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL29517550 | 0.81 | FFAR4 (0.38) | FFAR4PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL24439602 | 0.80 | FFAR4 (0.37) | FFAR4APPPDE4APDE4DPDE4B | |
| SCHEMBL15903786 | 0.74 | CSNK2A1 (0.47) | PDE4APDE4DPDE4BPDE4CCSNK2A1 | |
| SCHEMBL15904183 | 0.73 | CSNK2A1 (0.48) | PDE4APDE4DPDE4BPDE4CCSNK2A1 | |
| SCHEMBL24439314 | 0.72 | LPAR1 (0.33) | PDE4APDE4DPDE4BPDE4CCSNK2A1 | |
| SCHEMBL29672126 | 0.72 | LPAR1 (0.33) | PDE4APDE4DPDE4BPDE4CCSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022100624-A1 | OXY-SUBSTITUTED AMINOCARBONATE THIOPHENE-BASED COMPOUND AND USE THEREOF | 武汉人福创新药物研发中心有限公司 | 2022-05-19 | — | — | WO | disclosed |