Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC3 | O15438 | 2/20 | 0.39 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.39 |
| ▸ | SLCO1B3 | Q9NPD5 | 2/20 | 0.39 |
| ▸ | SLCO1B1 | Q9Y6L6 | 2/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
| ▸ | KMO | O15229 | 3/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29672312 | 1.00 | ABCC3 (0.39) | ABCC3ABCC4SLCO1B3SLCO1B1ABCB11 | |
| SCHEMBL24439399 | 0.90 | SLCO1B1 (0.52) | ABCC3ABCC4SLCO1B3SLCO1B1ABCB11 | |
| SCHEMBL29672229 | 0.90 | SLCO1B1 (0.52) | ABCC3ABCC4SLCO1B3SLCO1B1ABCB11 | |
| SCHEMBL24439645 | 0.90 | SLCO1B1 (0.42) | ABCC3ABCC4SLCO1B3SLCO1B1ABCB11 | |
| SCHEMBL24439614 | 0.89 | SLCO1B1 (0.44) | ABCC3ABCC4SLCO1B3SLCO1B1ABCB11 | |
| SCHEMBL29517320 | 0.89 | SLCO1B1 (0.44) | ABCC3ABCC4SLCO1B3SLCO1B1ABCB11 | |
| SCHEMBL24439463 | 0.89 | SLCO1B1 (0.42) | ABCC3ABCC4SLCO1B3SLCO1B1ABCB11 | |
| SCHEMBL24439719 | 0.89 | SLCO1B1 (0.48) | ABCC3ABCC4SLCO1B3SLCO1B1ABCB11 | |
| SCHEMBL24439381 | 0.89 | SLCO1B1 (0.50) | ABCC3ABCC4SLCO1B3SLCO1B1ABCB11 | |
| SCHEMBL24439366 | 0.88 | SLCO1B1 (0.51) | ABCC3ABCC4SLCO1B3SLCO1B1ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022100624-A1 | OXY-SUBSTITUTED AMINOCARBONATE THIOPHENE-BASED COMPOUND AND USE THEREOF | 武汉人福创新药物研发中心有限公司 | 2022-05-19 | — | — | WO | disclosed |