Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLCO1B1 | Q9Y6L6 | 8/20 | 0.44 |
| ▸ | LPAR1 | Q92633 | 6/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.44 |
| ▸ | ABCC3 | O15438 | 2/20 | 0.44 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.44 |
| ▸ | SLCO1B3 | Q9NPD5 | 2/20 | 0.44 |
| ▸ | RORC | P51449 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24439652 | 0.88 | SLCO1B1 (0.48) | SLCO1B1LPAR1ABCB11ABCC3ABCC4 | |
| SCHEMBL24439588 | 0.88 | SLCO1B1 (0.48) | SLCO1B1LPAR1ABCB11ABCC3ABCC4 | |
| SCHEMBL24439653 | 0.84 | SLCO1B1 (0.44) | SLCO1B1LPAR1ABCB11ABCC3ABCC4 | |
| SCHEMBL24439398 | 0.84 | SLCO1B1 (0.46) | SLCO1B1LPAR1ABCB11ABCC3ABCC4 | |
| SCHEMBL28744808 | 0.84 | LPAR1 (0.46) | SLCO1B1LPAR1ABCB11ABCC3ABCC4 | |
| SCHEMBL28744705 | 0.83 | LPAR1 (0.47) | SLCO1B1LPAR1ABCB11ABCC3ABCC4 | |
| SCHEMBL28744676 | 0.83 | LPAR1 (0.47) | SLCO1B1LPAR1ABCB11ABCC3ABCC4 | |
| SCHEMBL24439383 | 0.82 | SLCO1B1 (0.51) | SLCO1B1LPAR1ABCB11ABCC3ABCC4 | |
| SCHEMBL24439402 | 0.82 | SLCO1B1 (0.56) | SLCO1B1LPAR1ABCB11ABCC3ABCC4 | |
| SCHEMBL29672271 | 0.82 | SLCO1B1 (0.56) | SLCO1B1LPAR1ABCB11ABCC3ABCC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022100624-A1 | OXY-SUBSTITUTED AMINOCARBONATE THIOPHENE-BASED COMPOUND AND USE THEREOF | 武汉人福创新药物研发中心有限公司 | 2022-05-19 | — | — | WO | disclosed |