Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLCO1B1 | Q9Y6L6 | 7/20 | 0.48 |
| ▸ | ABCC3 | O15438 | 2/20 | 0.48 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.48 |
| ▸ | SLCO1B3 | Q9NPD5 | 2/20 | 0.48 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.46 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29517382 | 1.00 | SLCO1B1 (0.48) | SLCO1B1ABCC3ABCC4SLCO1B3ABCB11 | |
| SCHEMBL24439494 | 0.94 | SLCO1B1 (0.55) | SLCO1B1ABCC3ABCC4SLCO1B3ABCB11 | |
| SCHEMBL29517661 | 0.94 | SLCO1B1 (0.55) | SLCO1B1ABCC3ABCC4SLCO1B3ABCB11 | |
| SCHEMBL29517412 | 0.93 | SLCO1B1 (0.51) | SLCO1B1ABCC3ABCC4SLCO1B3ABCB11 | |
| SCHEMBL24439582 | 0.93 | SLCO1B1 (0.51) | SLCO1B1ABCC3ABCC4SLCO1B3ABCB11 | |
| SCHEMBL24439365 | 0.93 | SLCO1B1 (0.55) | SLCO1B1ABCC3ABCC4SLCO1B3ABCB11 | |
| SCHEMBL29672271 | 0.92 | SLCO1B1 (0.56) | SLCO1B1ABCC3ABCC4SLCO1B3ABCB11 | |
| SCHEMBL24439402 | 0.92 | SLCO1B1 (0.56) | SLCO1B1ABCC3ABCC4SLCO1B3ABCB11 | |
| SCHEMBL24439619 | 0.92 | SLCO1B1 (0.50) | SLCO1B1ABCC3ABCC4SLCO1B3ABCB11 | |
| SCHEMBL29517808 | 0.92 | SLCO1B1 (0.50) | SLCO1B1ABCC3ABCC4SLCO1B3ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022100624-A1 | OXY-SUBSTITUTED AMINOCARBONATE THIOPHENE-BASED COMPOUND AND USE THEREOF | 武汉人福创新药物研发中心有限公司 | 2022-05-19 | — | — | WO | disclosed |