SCHEMBL2444005

SCHEMBL2444005

Cc1cc(C2(c3ccc(Oc4cc(N)ccc4C(C)(C)C)c(C)c3)c3ccccc3-c3ccccc32)ccc1Oc1cc(N)ccc1C(C)(C)C

nearest known ligand 0.45

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.45
ESR2 Q92731 1/20 0.45
KDM4E B2RXH2 1/20 0.44
MEN1 O00255 1/20 0.44
LMNA P02545 1/20 0.44
MAPT P10636 1/20 0.44
OPRK1 P41145 1/20 0.44
KMT2A Q03164 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
PDK2 Q15119 2/20 0.34
PLA2G7 Q13093 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2448875 0.92 ESR1 (0.46) ESR1ESR2KDM4EMEN1LMNA
SCHEMBL2448288 0.90 ESR1 (0.44) ESR1ESR2KDM4EMEN1LMNA
SCHEMBL2444218 0.89 KDM4E (0.46) ESR1ESR2KDM4EMEN1LMNA
SCHEMBL29418365 0.89 KDM4E (0.46) ESR1ESR2KDM4EMEN1LMNA
SCHEMBL2445179 0.88 MAPT (0.54) ESR1ESR2KDM4EMEN1LMNA
SCHEMBL29418392 0.88 MAPT (0.54) ESR1ESR2KDM4EMEN1LMNA
SCHEMBL2440305 0.87 MEN1 (0.50) ESR1ESR2KDM4EMEN1LMNA
SCHEMBL2445382 0.84 KDM4E (0.50) ESR1ESR2KDM4EMEN1LMNA
SCHEMBL2445421 0.84 ESR1 (0.45) ESR1ESR2KDM4EMEN1LMNA
SCHEMBL2443588 0.83 ESR1 (0.44) ESR1ESR2KDM4EMEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11680140-B2 Particle-dispersed polyimide precursor solution, method for producing porous polyimide film, and porous polyimide film FUJIFILM BUSINESS INNOVATION CORP. (JP) 2023-06-20 US disclosed
US-20220064379-A1 PARTICLE-DISPERSED POLYIMIDE PRECURSOR SOLUTION, METHOD FOR PRODUCING POROUS POLYIMIDE FILM, AND POROUS POLYIMIDE FILM FUJIFILM BUSINESS INNOVATION CORP. (JP) 2022-03-03 US disclosed
EP-2128193-B1 POROUS POLYIMIDE IBIDEN CO LTD (JP) 2013-06-19 EP disclosed
US-8022110-B2 Porous polyimide IBIDEN CO., LTD. (JP) 2011-09-20 US disclosed
US-20100048745-A1 POROUS POLYIMIDE IBIDEN CO., LTD (JP) 2010-02-25 US disclosed
EP-2128193-A1 POROUS POLYIMIDE Ibiden Co., Ltd. (JP) 2009-12-02 EP disclosed