Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22221406 | 0.85 | ATM (0.36) | CCR2 | |
| SCHEMBL22511973 | 0.85 | ATM (0.36) | CCR2 | |
| SCHEMBL7489016 | 0.77 | KMT2A (0.33) | — | |
| SCHEMBL7443702 | 0.77 | KMT2A (0.33) | — | |
| SCHEMBL1914601 | 0.77 | KMT2A (0.33) | — | |
| SCHEMBL883190 | 0.75 | PEPD (0.34) | CCR2 | |
| SCHEMBL24327073 | 0.75 | PEPD (0.34) | CCR2 | |
| SCHEMBL1914633 | 0.75 | NR1H2 (0.42) | — | |
| SCHEMBL1914221 | 0.75 | NR1H2 (0.42) | — | |
| SCHEMBL116548 | 0.75 | NR1H2 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022100710-A1 | TYROSINE KINASE 2 (TYK2) DEGRADATION COMPOUNDS AND METHODS OF USE | CULLGEN (SHANGHAI) , INC. (CN) | 2022-05-19 | — | — | WO | disclosed |