SCHEMBL24444142

SCHEMBL24444142

N#CCCOP1(=S)OC[C@H]2C[C@@H](n3cnc4c(=O)n5ccn(CCc6ccc([N+](=O)[O-])cc6)c5nc43)[C@@H]2COP(=O)(S)OC[C@H]2O[C@@H](n3cnc4c(NC(=O)c5ccccc5)ncnc43)C[C@@H]2O1

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ SLC29A1 Q99808 1/20 0.32
▸ STING1 Q86WV6 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21263831 0.95 SLC29A1 (0.34) SLC29A1
SCHEMBL21263916 0.83 STING1 (0.35) STING1
SCHEMBL25688763 0.78 STING1 (0.41) STING1
SCHEMBL20691351 0.78 STING1 (0.44) STING1
SCHEMBL22349195 0.78 STING1 (0.35) STING1
SCHEMBL21264010 0.76 STING1 (0.34) STING1
SCHEMBL20691310 0.74 STING1 (0.40) SLC29A1STING1
SCHEMBL25688781 0.74 STING1 (0.43) STING1
SCHEMBL24321999 0.72 SLC29A1 (0.37) SLC29A1
SCHEMBL24322109 0.72 STING1 (0.34) SLC29A1STING1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11339185-B2 Cyclic dinucleotides as anticancer agents BRISTOL-MYERS SQUIBB COMPANY (US) 2022-05-24 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11339185-B2 Cyclic dinucleotides as anticancer agents DPYD, NTPCR, CD38 SLC29A1 537/4885STING1 142/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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