Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24445686 | 0.92 | NR1H4 (0.75) | NR1H4HSD17B13 | |
| SCHEMBL24519844 | 0.90 | NR1H4 (0.84) | NR1H4HSD17B13 | |
| SCHEMBL19698939 | 0.90 | NR1H4 (0.91) | NR1H4HSD17B13 | |
| SCHEMBL19689514 | 0.86 | NR1H4 (1.00) | NR1H4HSD17B13 | |
| SCHEMBL29760423 | 0.86 | NR1H4 (1.00) | NR1H4HSD17B13 | |
| SCHEMBL19698940 | 0.84 | NR1H4 (0.88) | NR1H4HSD17B13 | |
| SCHEMBL20749569 | 0.84 | NR1H4 (0.77) | NR1H4HSD17B13 | |
| SCHEMBL25724183 | 0.83 | NR1H4 (0.73) | NR1H4HSD17B13 | |
| SCHEMBL29139864 | 0.83 | NR1H4 (0.71) | NR1H4HSD17B13 | |
| SCHEMBL24445677 | 0.83 | NR1H4 (0.63) | NR1H4HSD17B13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3587412-B1 | FXR (NR1H4) MODULATING COMPOUNDS | GILEAD SCIENCES INC (US) | 2022-05-25 | — | — | EP | disclosed |