Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 20/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24446021 | 0.90 | ADORA2A (0.75) | ADORA2A | |
| SCHEMBL24445775 | 0.89 | ADORA2A (0.77) | ADORA2A | |
| SCHEMBL21887098 | 0.89 | ADORA2A (0.75) | ADORA2A | |
| SCHEMBL24445980 | 0.88 | ADORA2A (0.72) | ADORA2A | |
| SCHEMBL25565137 | 0.88 | ADORA2A (0.76) | ADORA2A | |
| SCHEMBL25541278 | 0.88 | ADORA2A (0.74) | ADORA2A | |
| SCHEMBL20522124 | 0.88 | ADORA2A (0.71) | ADORA2A | |
| SCHEMBL20521505 | 0.88 | ADORA2A (0.77) | ADORA2A | |
| SCHEMBL24445769 | 0.88 | ADORA2A (0.73) | ADORA2A | |
| SCHEMBL20521715 | 0.87 | ADORA2A (0.70) | ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3601296-B1 | 2-OXO-THIAZOLE DERIVATIVES AS A2A INHIBITORS AND COMPOUNDS FOR USE IN THE TREATMENT OF CANCERS | iTeos Belgium SA (BE) | 2022-05-25 | — | — | EP | disclosed |