SCHEMBL24446352

SCHEMBL24446352

CN(C)c1ccc(-c2ccc(/C=C/C3=[N+](CCCCS)c4ccc5ccccc5c4C3(C)C)s2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRMT1 Q99873 9/20 0.41
PRMT5 O14744 1/20 0.41
PRMT8 Q9NR22 1/20 0.41
BLM P54132 2/20 0.39
MLNR O43193 1/20 0.37
NR1I2 O75469 1/20 0.37
PGR P06401 1/20 0.37
ADRB1 P08588 1/20 0.37
ADORA3 P0DMS8 1/20 0.37
CHRM1 P11229 1/20 0.37
DRD2 P14416 1/20 0.37
ADRA2B P18089 1/20 0.37
ADRA2C P18825 1/20 0.37
CHRM3 P20309 1/20 0.37
CNR1 P21554 1/20 0.37
DRD1 P21728 1/20 0.37
TBXA2R P21731 1/20 0.37
SLC6A2 P23975 1/20 0.37
HRH2 P25021 1/20 0.37
HTR2C P28335 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24446350 0.98 PRMT1 (0.41) PRMT1PRMT5PRMT8BLMMLNR
SCHEMBL24437463 0.88 MLNR (0.50) PRMT1PRMT5PRMT8BLMMLNR
SCHEMBL29683885 0.88 BLM (0.52) PRMT1PRMT5PRMT8BLMMLNR
SCHEMBL28736058 0.88 BLM (0.52) PRMT1PRMT5PRMT8BLMMLNR
SCHEMBL24446462 0.87 PRMT1 (0.41) PRMT1PRMT5PRMT8BLMMLNR
SCHEMBL31687205 0.87 BLM (0.51) PRMT1PRMT5PRMT8BLMMLNR
SCHEMBL24437464 0.87 MLNR (0.49) PRMT1PRMT5PRMT8BLMMLNR
SCHEMBL24446420 0.85 MAPT (0.44) PRMT1PRMT5PRMT8BLMMLNR
SCHEMBL24437466 0.77 MLNR (0.51) PRMT1PRMT5PRMT8BLMMLNR
SCHEMBL29683791 0.77 BLM (0.53) PRMT1PRMT5PRMT8BLMMLNR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4001264-A1 WATER-SOLUBLE COMPOUND FOR DETECTION OF BETA-AMYLOID Korea Atomic Energy Research Institute (KR) 2022-05-25 EP disclosed