Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.60 |
| ▸ | CTSL | P07711 | 4/20 | 0.51 |
| ▸ | CTSB | P07858 | 4/20 | 0.51 |
| ▸ | CTSS | P25774 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28951850 | 0.88 | KMT2A (0.55) | KMT2AMEN1RCE1CTSLCTSB | |
| SCHEMBL25232548 | 0.88 | KMT2A (0.58) | KMT2AMEN1RCE1CTSLCTSB | |
| SCHEMBL25533122 | 0.88 | KMT2A (0.55) | KMT2AMEN1RCE1CTSLCTSB | |
| SCHEMBL25232550 | 0.88 | KMT2A (0.58) | KMT2AMEN1RCE1CTSLCTSB | |
| SCHEMBL30174726 | 0.88 | KMT2A (0.55) | KMT2AMEN1RCE1CTSLCTSB | |
| SCHEMBL24113263 | 0.87 | KMT2A (0.54) | KMT2AMEN1RCE1CTSLCTSB | |
| SCHEMBL24029304 | 0.86 | KMT2A (0.53) | KMT2AMEN1RCE1CTSLCTSB | |
| SCHEMBL28951469 | 0.85 | MEN1 (0.55) | KMT2AMEN1RCE1CTSLCTSB | |
| SCHEMBL23836099 | 0.83 | KMT2A (0.77) | KMT2AMEN1RCE1CTSLCTSB | |
| SCHEMBL25789783 | 0.82 | KMT2A (0.69) | KMT2AMEN1RCE1NPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4001279-A1 | NOVEL SPIROPYRROLIDINE DERIVED ANTIVIRAL AGENTS | Enanta Pharmaceuticals, Inc. (US) | 2022-05-25 | — | — | EP | disclosed |