Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 14/20 | 0.67 |
| ▸ | ACHE | P22303 | 6/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30820022 | 1.00 | STING1 (0.67) | STING1ACHE | |
| SCHEMBL24451326 | 1.00 | STING1 (0.67) | STING1ACHE | |
| SCHEMBL25694251 | 0.90 | STING1 (0.69) | STING1ACHE | |
| SCHEMBL29976117 | 0.90 | STING1 (0.69) | STING1ACHE | |
| SCHEMBL21452607 | 0.90 | STING1 (0.64) | STING1ACHE | |
| SCHEMBL30820009 | 0.90 | STING1 (0.81) | STING1ACHE | |
| SCHEMBL20022337 | 0.90 | STING1 (0.81) | STING1ACHE | |
| SCHEMBL28903393 | 0.87 | STING1 (0.51) | STING1ACHE | |
| SCHEMBL21452766 | 0.86 | STING1 (0.57) | STING1ACHE | |
| SCHEMBL21422968 | 0.86 | STING1 (0.81) | STING1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118108716-A | Benzothiophene compound and preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2024-05-31 | — | — | CN | disclosed |
| CN-113518776-B | Benzothiophene compound and preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2024-03-26 | — | — | CN | disclosed |
| US-20220162199-A1 | BENZOTHIOPHENE COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD. (CN) | 2022-05-26 | — | — | US | disclosed |
| CN-113518776-A | Benzothiophenes, process for their preparation and their use | 四川科伦博泰生物医药股份有限公司 | 2021-10-19 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220162199-A1 | BENZOTHIOPHENE COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | STING1, CYP11B1, CYP4A11 | STING1 1/4885ACHE 3229/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.