Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 19/20 | 0.49 |
| ▸ | HCRTR2 | O43614 | 9/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2447344 | 0.93 | HCRTR1 (0.56) | HCRTR1HCRTR2 | |
| SCHEMBL2444527 | 0.93 | HCRTR1 (0.57) | HCRTR1HCRTR2 | |
| SCHEMBL2444688 | 0.92 | HCRTR1 (0.49) | HCRTR1HCRTR2 | |
| SCHEMBL2446890 | 0.90 | HCRTR1 (0.52) | HCRTR1HCRTR2KDM4EALDH1A1HPGD | |
| SCHEMBL496413 | 0.89 | HCRTR1 (0.59) | HCRTR1HCRTR2 | |
| SCHEMBL2449460 | 0.88 | HCRTR1 (0.51) | HCRTR1HCRTR2 | |
| SCHEMBL2442099 | 0.87 | HCRTR1 (0.57) | HCRTR1HCRTR2 | |
| SCHEMBL2446979 | 0.86 | HCRTR1 (0.56) | HCRTR1HCRTR2 | |
| SCHEMBL2445354 | 0.86 | HCRTR1 (0.50) | HCRTR1HCRTR2 | |
| SCHEMBL2446189 | 0.86 | HCRTR1 (0.49) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2164847-B1 | 3-AZA-BICYCLO[3.3.0]OCTANE COMPOUNDS | ACTELION PHARMACEUTICALS LTD (CH) | 2011-09-14 | — | — | EP | claimed |