Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 20/20 | 0.47 |
| ▸ | EGFR | P00533 | 3/20 | 0.46 |
| ▸ | TEC | P42680 | 1/20 | 0.43 |
| ▸ | BMX | P51813 | 1/20 | 0.43 |
| ▸ | CD69 | Q07108 | 1/20 | 0.43 |
| ▸ | ITK | Q08881 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.43 |
| ▸ | GP6 | Q9HCN6 | 1/20 | 0.43 |
| ▸ | NUDT5 | Q9UKK9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31523730 | 1.00 | BTK (0.47) | BTKEGFRTECBMXCD69 | |
| SCHEMBL24458882 | 0.90 | BTK (0.49) | BTKEGFRTECBMXCD69 | |
| SCHEMBL24458294 | 0.90 | BTK (0.57) | BTKEGFRTECBMXCD69 | |
| SCHEMBL24458918 | 0.90 | ITK (0.44) | BTKEGFRITK | |
| SCHEMBL31523935 | 0.90 | ITK (0.44) | BTKEGFRITK | |
| SCHEMBL31523765 | 0.89 | BTK (0.49) | BTKEGFRTECBMXCD69 | |
| SCHEMBL24458315 | 0.89 | BTK (0.49) | BTKEGFRTECBMXCD69 | |
| SCHEMBL24458778 | 0.89 | BTK (0.48) | BTKEGFRTECBMXCD69 | |
| SCHEMBL24458689 | 0.88 | BTK (0.45) | BTKEGFRTECBMXCD69 | |
| SCHEMBL31523772 | 0.88 | BTK (0.45) | BTKEGFRTECBMXCD69 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022109551-A1 | SRC INHIBITORS AND USES THEREOF | RELAY THERAPEUTICS, INC. (US) | 2022-05-27 | — | — | WO | disclosed |