Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 15/20 | 0.53 |
| ▸ | EGFR | P00533 | 8/20 | 0.53 |
| ▸ | LCK | P06239 | 6/20 | 0.53 |
| ▸ | ITK | Q08881 | 3/20 | 0.53 |
| ▸ | JAK3 | P52333 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 2/20 | 0.46 |
| ▸ | TEK | Q02763 | 2/20 | 0.46 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.44 |
| ▸ | FGFR4 | P22455 | 2/20 | 0.44 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.44 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24458509 | 0.97 | BTK (0.52) | BTKEGFRLCKITKJAK3 | |
| SCHEMBL24458383 | 0.94 | BTK (0.52) | BTKEGFRLCKITKJAK3 | |
| SCHEMBL24459023 | 0.94 | BTK (0.48) | BTKEGFRLCKITKJAK3 | |
| SCHEMBL24458390 | 0.93 | BTK (0.56) | BTKEGFRLCKITKJAK3 | |
| SCHEMBL24458906 | 0.92 | BTK (0.51) | BTKEGFRLCKITKJAK3 | |
| SCHEMBL24458565 | 0.91 | BTK (0.64) | BTKEGFRLCKITKJAK3 | |
| SCHEMBL24458801 | 0.91 | BTK (0.54) | BTKEGFRLCKITKJAK3 | |
| SCHEMBL24458471 | 0.91 | BTK (0.53) | BTKEGFRLCKITKJAK3 | |
| SCHEMBL31523877 | 0.90 | BTK (0.51) | BTKEGFRLCKITKJAK3 | |
| Formic Acid SCHEMBL31523827 | 0.89 | BTK (0.52) | BTKEGFRLCKITKJAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022109551-A1 | SRC INHIBITORS AND USES THEREOF | RELAY THERAPEUTICS, INC. (US) | 2022-05-27 | — | — | WO | disclosed |