SCHEMBL24458488 — predicted protein targets

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	FGFR1	P11362	5/20	0.41

▸	FGFR4	P22455	5/20	0.41

▸	FGFR2	P21802	7/20	0.41

▸	BTK	Q06187	7/20	0.40

▸	KDR	P35968	3/20	0.39

▸	FGFR3	P22607	1/20	0.39

▸	ITK	Q08881	2/20	0.39

▸	EGFR	P00533	1/20	0.39

▸	ERBB2	P04626	1/20	0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL31523771	1.00	FGFR1 (0.41)	FGFR1FGFR4FGFR2BTKKDR
SCHEMBL24458487	0.91	FGFR2 (0.45)	FGFR1FGFR4FGFR2BTKKDR
SCHEMBL31523728	0.89	FGFR4 (0.47)	FGFR1FGFR4FGFR2BTKKDR
SCHEMBL24459074	0.89	FGFR4 (0.47)	FGFR1FGFR4FGFR2BTKKDR
SCHEMBL24458378	0.86	FGFR1 (0.42)	FGFR1FGFR4FGFR2BTKKDR
SCHEMBL24458503	0.86	RET (0.45)	FGFR1FGFR4FGFR2BTKKDR
SCHEMBL31523837	0.86	RET (0.45)	FGFR1FGFR4FGFR2BTKKDR
SCHEMBL24458531	0.86	RET (0.45)	FGFR1FGFR4FGFR2BTKKDR
SCHEMBL24458475	0.86	FGFR2 (0.42)	FGFR1FGFR4FGFR2BTKKDR
SCHEMBL29552790	0.86	FGFR2 (0.42)	FGFR1FGFR4FGFR2BTKKDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2022109551-A1	SRC INHIBITORS AND USES THEREOF	RELAY THERAPEUTICS, INC. (US)	2022-05-27	—	—	WO	disclosed