Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 20/20 | 0.57 |
| ▸ | EGFR | P00533 | 5/20 | 0.57 |
| ▸ | TEC | P42680 | 4/20 | 0.51 |
| ▸ | BMX | P51813 | 4/20 | 0.51 |
| ▸ | ITK | Q08881 | 3/20 | 0.51 |
| ▸ | TXK | P42681 | 2/20 | 0.51 |
| ▸ | LYN | P07948 | 2/20 | 0.51 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.51 |
| ▸ | ERBB4 | Q15303 | 2/20 | 0.51 |
| ▸ | GP6 | Q9HCN6 | 2/20 | 0.51 |
| ▸ | NUDT5 | Q9UKK9 | 2/20 | 0.51 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.51 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.51 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.51 |
| ▸ | LATS1 | O95835 | 1/20 | 0.51 |
| ▸ | NUDT14 | O95848 | 1/20 | 0.51 |
| ▸ | ABL1 | P00519 | 1/20 | 0.51 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.51 |
| ▸ | LCK | P06239 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formic Acid SCHEMBL31523925 | 0.98 | BTK (0.55) | BTKEGFRTECBMXITK | |
| SCHEMBL24458654 | 0.96 | BTK (0.59) | BTKEGFRTECBMXITK | |
| SCHEMBL24458924 | 0.93 | BTK (0.57) | BTKEGFRTECBMXITK | |
| SCHEMBL24458617 | 0.93 | BTK (0.58) | BTKEGFRTECBMXITK | |
| SCHEMBL24458619 | 0.93 | BTK (0.59) | BTKEGFRTECBMXITK | |
| SCHEMBL24458627 | 0.92 | BTK (0.60) | BTKEGFRTECBMXITK | |
| SCHEMBL24458566 | 0.90 | BTK (0.57) | BTKEGFRTECBMXITK | |
| SCHEMBL24458467 | 0.89 | BTK (0.54) | BTKEGFRTECBMXITK | |
| SCHEMBL31523896 | 0.89 | BTK (0.54) | BTKEGFRTECBMXITK | |
| SCHEMBL24458388 | 0.88 | BTK (0.55) | BTKEGFRTECBMXITK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022109551-A1 | SRC INHIBITORS AND USES THEREOF | RELAY THERAPEUTICS, INC. (US) | 2022-05-27 | — | — | WO | disclosed |