Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITK | Q08881 | 1/20 | 0.48 |
| ▸ | FGFR4 | P22455 | 11/20 | 0.46 |
| ▸ | FGFR1 | P11362 | 10/20 | 0.46 |
| ▸ | FGFR2 | P21802 | 11/20 | 0.45 |
| ▸ | FGFR3 | P22607 | 4/20 | 0.45 |
| ▸ | KDR | P35968 | 4/20 | 0.44 |
| ▸ | BTK | Q06187 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31523779 | 1.00 | ITK (0.48) | ITKFGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL24458360 | 0.95 | ITK (0.54) | ITKFGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL31523744 | 0.91 | ITK (0.49) | ITKFGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL24458973 | 0.91 | ITK (0.49) | ITKFGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL24458633 | 0.91 | ITK (0.46) | ITKFGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL31523912 | 0.91 | ITK (0.46) | ITKFGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL24458601 | 0.90 | RET (0.49) | ITKFGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL24459042 | 0.90 | BTK (0.50) | ITKFGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL24458998 | 0.89 | FGFR4 (0.47) | ITKFGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL31523968 | 0.89 | FGFR4 (0.47) | ITKFGFR4FGFR1FGFR2FGFR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022109551-A1 | SRC INHIBITORS AND USES THEREOF | RELAY THERAPEUTICS, INC. (US) | 2022-05-27 | — | — | WO | disclosed |