Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 10/20 | 0.53 |
| ▸ | DDB1 | Q16531 | 8/20 | 0.53 |
| ▸ | STAT3 | P40763 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | SNCA | P37840 | 1/20 | 0.47 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.46 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.46 |
| ▸ | FOXM1 | Q08050 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24142096 | 1.00 | CRBN (0.53) | CRBNDDB1STAT3HDAC1HDAC6 | |
| Hydrochloric Acid SCHEMBL30893199 | 0.99 | CRBN (0.52) | CRBNDDB1STAT3HDAC1HDAC6 | |
| Hydrochloric Acid SCHEMBL30893273 | 0.99 | CRBN (0.52) | CRBNDDB1STAT3HDAC1HDAC6 | |
| SCHEMBL27346400 | 0.92 | CRBN (0.54) | CRBNDDB1STAT3HDAC1HDAC6 | |
| SCHEMBL27346366 | 0.92 | CRBN (0.54) | CRBNDDB1STAT3HDAC1HDAC6 | |
| SCHEMBL27346376 | 0.92 | CRBN (0.54) | CRBNDDB1STAT3HDAC1HDAC6 | |
| SCHEMBL27208479 | 0.92 | CRBN (0.53) | CRBNDDB1STAT3HDAC1HDAC6 | |
| SCHEMBL30822371 | 0.92 | CRBN (0.53) | CRBNDDB1STAT3HDAC1HDAC6 | |
| SCHEMBL27346364 | 0.92 | CRBN (0.53) | CRBNDDB1STAT3HDAC1HDAC6 | |
| SCHEMBL30751218 | 0.91 | CRBN (0.55) | CRBNDDB1STAT3HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022109396-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2022-05-27 | — | — | WO | disclosed |