Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 13/20 | 0.48 |
| ▸ | EGFR | P00533 | 7/20 | 0.47 |
| ▸ | LCK | P06239 | 5/20 | 0.47 |
| ▸ | ITK | Q08881 | 4/20 | 0.47 |
| ▸ | FGFR2 | P21802 | 6/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.44 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.44 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31523955 | 1.00 | BTK (0.48) | BTKEGFRLCKITKFGFR2 | |
| SCHEMBL24458649 | 0.91 | BTK (0.38) | BTKEGFRLCKITKFGFR2 | |
| SCHEMBL31523722 | 0.91 | BTK (0.38) | BTKEGFRLCKITKFGFR2 | |
| SCHEMBL24459135 | 0.91 | BTK (0.58) | BTKEGFRLCKITKFGFR2 | |
| SCHEMBL31523866 | 0.90 | FGFR2 (0.45) | BTKEGFRLCKITKFGFR2 | |
| SCHEMBL24458738 | 0.90 | FGFR2 (0.45) | BTKEGFRLCKITKFGFR2 | |
| SCHEMBL31524014 | 0.89 | FGFR2 (0.46) | BTKEGFRLCKITKFGFR2 | |
| SCHEMBL24458665 | 0.89 | FGFR2 (0.46) | BTKEGFRLCKITKFGFR2 | |
| SCHEMBL24458507 | 0.89 | BTK (0.46) | BTKEGFRLCKITKFGFR2 | |
| SCHEMBL31523860 | 0.89 | BTK (0.46) | BTKEGFRLCKITKFGFR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022109551-A1 | SRC INHIBITORS AND USES THEREOF | RELAY THERAPEUTICS, INC. (US) | 2022-05-27 | — | — | WO | disclosed |