SCHEMBL2445907

SCHEMBL2445907

O=[C]c1cc(Br)c(Br)s1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3194023 0.76
SCHEMBL12496399 0.75
SCHEMBL9769048 0.65
SCHEMBL16798610 0.64 GSK3B (0.39)
SCHEMBL917122 0.64
SCHEMBL6454958 0.62
SCHEMBL1660167 0.62
SCHEMBL20448726 0.60
SCHEMBL947395 0.60
SCHEMBL20448768 0.60

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3356387-B1 ANTIMICROBIAL POLYMYXIN DERIVATIVE COMPOUNDS UNIV MONASH (AU) 2024-06-26 EP claimed
US-11225505-B2 Antimicrobial polymyxin derivative compounds MONASH UNIVERSITY (AU) 2022-01-18 US claimed
CN-110669107-A Antibacterial peptide and preparation method thereof 上海医药工业研究院 2020-01-10 CN claimed
US-20180282374-A1 ANTIMICROBIAL POLYMYXIN DERIVATIVE COMPOUNDS MONASH UNIVERSITY (AU) 2018-10-04 US claimed
EP-3356387-A1 ANTIMICROBIAL POLYMYXIN DERIVATIVE COMPOUNDS Monash University (AU) 2018-08-08 EP claimed
EP-3356387-B1 ANTIMICROBIAL POLYMYXIN DERIVATIVE COMPOUNDS UNIV MONASH (AU) 2024-06-26 EP disclosed
CN-110669107-B Antibacterial peptide and preparation method thereof 上海医药工业研究院 2024-04-02 CN disclosed
US-11225505-B2 Antimicrobial polymyxin derivative compounds MONASH UNIVERSITY (AU) 2022-01-18 US disclosed
CN-110669107-A Antibacterial peptide and preparation method thereof 上海医药工业研究院 2020-01-10 CN disclosed
US-20180282374-A1 ANTIMICROBIAL POLYMYXIN DERIVATIVE COMPOUNDS MONASH UNIVERSITY (AU) 2018-10-04 US disclosed
EP-3356387-A1 ANTIMICROBIAL POLYMYXIN DERIVATIVE COMPOUNDS Monash University (AU) 2018-08-08 EP disclosed
EP-1966147-B1 CARBOXAMIDES FOR CONTROLLING MICRO-ORGANISMS IN PLANT AND MATERIAL PROTECTION BAYER CROPSCIENCE AG (DE) 2012-08-08 EP disclosed
US-8017558-B2 Carboxamides for controlling micro-organisms in plant and material protection BAYER CROPSCIENCE AG (DE) 2011-09-13 US disclosed
US-20090247586-A1 CARBOXAMIDES FOR CONTROLLING MICRO-ORGANISMS IN PLANT AND MATERIAL PROTECTION BAYER CROPSCIENCE (DE) 2009-10-01 US disclosed
EP-1966147-A1 CARBOXAMIDES FOR CONTROLLING MICRO-ORGANISMS IN PLANT AND MATERIAL PROTECTION Bayer CropScience AG (DE) 2008-09-10 EP disclosed
WO-2007068377-A1 CARBOXAMIDES FOR CONTROLLING MICRO-ORGANISMS IN PLANT AND MATERIAL PROTECTION BAYER CROPSCIENCE AG (DE) 2007-06-21 WO disclosed