Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 19/20 | 0.69 |
| ▸ | VHL | P40337 | 1/20 | 0.47 |
| ▸ | CDK7 | P50613 | 1/20 | 0.47 |
| ▸ | CCNH | P51946 | 1/20 | 0.47 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.47 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23465147 | 1.00 | KRAS (0.69) | KRASVHLCDK7CCNHMNAT1 | |
| SCHEMBL19947678 | 0.90 | KRAS (0.70) | KRASVHLCDK7CCNHMNAT1 | |
| SCHEMBL23465151 | 0.89 | KRAS (0.71) | KRAS | |
| SCHEMBL23464871 | 0.87 | KRAS (0.68) | KRASVHLCDK7CCNHMNAT1 | |
| SCHEMBL24460025 | 0.87 | KRAS (0.68) | KRASVHLCDK7CCNHMNAT1 | |
| SCHEMBL19947689 | 0.86 | KRAS (0.65) | KRASVHLCDK7CCNHMNAT1 | |
| SCHEMBL30189104 | 0.86 | KRAS (0.65) | KRASVHLCDK7CCNHMNAT1 | |
| SCHEMBL21005433 | 0.86 | KRAS (0.74) | KRASVHLCDK7CCNHMNAT1 | |
| SCHEMBL24459962 | 0.86 | KRAS (0.62) | KRASVHLCDK7CCNHMNAT1 | |
| SCHEMBL22440239 | 0.85 | KRAS (0.77) | KRASVHLCDK7CCNHMNAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022106897-A2 | METHODS AND COMPOSITION FOR KRAS MODIFICATIONS | 2692372 ONTARIO, INC. (CA) | 2022-05-27 | — | — | WO | disclosed |