SCHEMBL24460282

SCHEMBL24460282

CC(C)Oc1ccc(-c2cnc3ccc(-c4cccc(OC(C)C)c4)nn23)cc1

nearest known ligand 0.63

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
FYN P06241 14/20 0.63
DYRK1A Q13627 4/20 0.57
KCNH2 Q12809 2/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24460284 0.95 FYN (0.61) FYNDYRK1AKCNH2
SCHEMBL19781269 0.89 FYN (0.58) FYNKCNH2
SCHEMBL24460469 0.84 FYN (0.53) FYN
SCHEMBL24460275 0.82 FYN (0.48) FYNKCNH2
SCHEMBL24460283 0.81 FYN (0.50) FYNDYRK1A
SCHEMBL24460281 0.80 FYN (0.48) FYN
SCHEMBL26361838 0.78 FYN (0.49) FYNDYRK1A
SCHEMBL19781794 0.78 DYRK1A (0.58) FYNDYRK1A
SCHEMBL18613750 0.77 FYN (1.00) FYNDYRK1A
SCHEMBL19781166 0.76 KCNH2 (0.47) FYNKCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230303569-A1 HETEROCYCLIC COMPOUNDS AS THERAPEUTIC AGENTS ARISAN THERAPEUTICS INC. (US) 2023-09-28 US disclosed
US-20230303569-A1 HETEROCYCLIC COMPOUNDS AS THERAPEUTIC AGENTS ARISAN THERAPEUTICS INC. (US) 2023-09-28 US disclosed
WO-2022108849-A1 HETEROCYCLIC COMPOUNDS AS THERAPEUTIC AGENTS ARISAN THERAPEUTICS INC. (US) 2022-05-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230303569-A1 HETEROCYCLIC COMPOUNDS AS THERAPEUTIC AGENTS C3AR1, C9, C1R FYN 1748/4885DYRK1A 4426/4885KCNH2 649/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.