Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.63 |
| ▸ | MEN1 | O00255 | 4/20 | 0.63 |
| ▸ | MAPT | P10636 | 3/20 | 0.63 |
| ▸ | NPC1 | O15118 | 2/20 | 0.63 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.63 |
| ▸ | PKM | P14618 | 1/20 | 0.63 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.63 |
| ▸ | PLAU | P00749 | 3/20 | 0.56 |
| ▸ | F10 | P00742 | 2/20 | 0.56 |
| ▸ | PLAT | P00750 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | TNF | P01375 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | POLA1 | P09884 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11762101 | 0.89 | KMT2A (0.67) | KMT2AMEN1MAPTNPC1HSP90AA1 | |
| SCHEMBL17699318 | 0.86 | KMT2A (0.74) | KMT2AMEN1MAPTNPC1HSP90AA1 | |
| SCHEMBL30771723 | 0.85 | P2RX1 (0.74) | KMT2AMEN1MAPTNPC1HSP90AA1 | |
| SCHEMBL26980210 | 0.85 | P2RX1 (0.74) | KMT2AMEN1MAPTNPC1HSP90AA1 | |
| SCHEMBL14363303 | 0.85 | P2RX1 (0.73) | KMT2AMEN1MAPTNPC1HSP90AA1 | |
| SCHEMBL11761577 | 0.80 | MEN1 (0.60) | KMT2AMEN1MAPTNPC1HSP90AA1 | |
| SCHEMBL11762111 | 0.80 | KMT2A (0.63) | KMT2AMEN1MAPTNPC1PKM | |
| SCHEMBL11764597 | 0.80 | SMN1; SMN2 (0.68) | KMT2AMEN1MAPTNPC1PKM | |
| SCHEMBL29617478 | 0.78 | KMT2A (0.78) | KMT2AMEN1MAPTNPC1PKM | |
| SCHEMBL16160831 | 0.78 | KMT2A (0.78) | KMT2AMEN1MAPTNPC1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022109148-A1 | SMALL MOLECULE INHIBITORS OF SARS-COV-2 INFECTIONS | THE USA, AS REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES (US) | 2022-05-27 | — | — | WO | disclosed |