SCHEMBL24460451

SCHEMBL24460451

CC/C=C(/N1CCNCC1)N1CCSc2ccc(OC(F)(F)F)cc2C1

nearest known ligand 0.53

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
RYR2 Q92736 20/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24460353 0.82 RYR2 (0.74) RYR2
SCHEMBL29564142 0.82 RYR2 (0.74) RYR2
Hydrochloric Acid SCHEMBL29563669 0.81 RYR2 (0.73) RYR2
SCHEMBL6884372 0.72 RYR2 (0.76) RYR2
SCHEMBL26942217 0.71 RYR2 (0.73) RYR2
SCHEMBL6866991 0.70 RYR2 (1.00) RYR2
SCHEMBL3427615 0.69 RYR2 (0.72) RYR2
SCHEMBL7999750 0.67 RYR2 (0.67) RYR2
SCHEMBL6867184 0.66 RYR2 (0.84) RYR2
SCHEMBL6866744 0.66 RYR2 (0.54) RYR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022108945-A1 AGENTS FOR TREATING DISORDERS INVOLVING RYANODINE RECEPTORS ARMGO PHARMA, INC. (US) 2022-05-27 WO disclosed