Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBRM1 | Q86U86 | 6/20 | 0.33 |
| ▸ | SMARCA2 | P51531 | 4/20 | 0.33 |
| ▸ | SMARCA4 | P51532 | 4/20 | 0.33 |
| ▸ | BTK | Q06187 | 2/20 | 0.33 |
| ▸ | AXL | P30530 | 7/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.31 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.30 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29619428 | 0.91 | AXL (0.32) | PBRM1SMARCA2SMARCA4BTKAXL | |
| SCHEMBL24461364 | 0.91 | AXL (0.32) | PBRM1SMARCA2SMARCA4BTKAXL | |
| SCHEMBL29619381 | 0.90 | AXL (0.35) | BTKAXL | |
| SCHEMBL24461404 | 0.90 | AXL (0.35) | BTKAXL | |
| SCHEMBL29619402 | 0.83 | AXL (0.33) | BTKAXLCAMKK2 | |
| SCHEMBL24461318 | 0.83 | AXL (0.33) | BTKAXLCAMKK2 | |
| SCHEMBL29619424 | 0.82 | AXL (0.37) | AXL | |
| SCHEMBL24461621 | 0.82 | AXL (0.37) | AXL | |
| SCHEMBL22777840 | 0.82 | PBRM1 (0.39) | PBRM1SMARCA2SMARCA4BTKNR1I2 | |
| SCHEMBL22777907 | 0.81 | PBRM1 (0.37) | PBRM1SMARCA2SMARCA4BTKCAMKK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022109426-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2022-05-27 | — | — | WO | disclosed |