⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5960685 | 0.72 | — | — | |
| SCHEMBL23335870 | 0.71 | — | — | |
| SCHEMBL22645140 | 0.70 | — | — | |
| SCHEMBL26007703 | 0.68 | — | — | |
| SCHEMBL20354875 | 0.68 | — | — | |
| SCHEMBL12175793 | 0.67 | — | — | |
| SCHEMBL20970105 | 0.65 | — | — | |
| SCHEMBL26519889 | 0.64 | — | — | |
| SCHEMBL24167188 | 0.61 | — | — | |
| SCHEMBL27103251 | 0.61 | PDPK1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3728221-B1 | AMIDE SUBSTITUTED INDOLE COMPOUNDS USEFUL AS TLR INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2022-06-01 | — | — | EP | disclosed |