Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21787515 | 0.77 | EGFR (0.32) | EGFR | |
| SCHEMBL23997975 | 0.77 | KDM4E (0.36) | KDM4E | |
| SCHEMBL22330419 | 0.77 | EGFR (0.32) | EGFR | |
| SCHEMBL9005243 | 0.76 | EGFR (0.41) | KDM4EACKR3EGFR | |
| SCHEMBL21914141 | 0.74 | KDM4E (0.33) | KDM4E | |
| SCHEMBL20322792 | 0.73 | KDM4E (0.34) | KDM4EEGFR | |
| SCHEMBL26074486 | 0.69 | CYP2D6 (0.33) | KDM4E | |
| SCHEMBL16610028 | 0.69 | — | — | |
| SCHEMBL14138758 | 0.69 | — | — | |
| SCHEMBL19954662 | 0.69 | MEN1 (0.33) | EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4006035-A1 | QUINAZOLINE DERIVATIVES AS TYROSINE KINASE INHIBITORS FOR THE TREATMENT OF CANCER | Neupharma, Inc. (US) | 2022-06-01 | — | — | EP | disclosed |