Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2446474 | 1.00 | KCNH2 (0.40) | KCNH2SLC2A1 | |
| SCHEMBL1076723 | 0.89 | KCNH2 (0.41) | KCNH2SLC2A1 | |
| SCHEMBL2444813 | 0.88 | KCNH2 (0.38) | KCNH2SLC2A1 | |
| SCHEMBL2444809 | 0.88 | KCNH2 (0.38) | KCNH2SLC2A1 | |
| SCHEMBL1267921 | 0.85 | SLC2A1 (0.40) | KCNH2SLC2A1 | |
| SCHEMBL1267923 | 0.84 | KCNH2 (0.46) | KCNH2SLC2A1 | |
| SCHEMBL1266474 | 0.83 | KCNH2 (0.36) | KCNH2SLC2A1 | |
| SCHEMBL1266395 | 0.82 | KDM2B (0.38) | KCNH2SLC2A1 | |
| SCHEMBL1267066 | 0.80 | KCNH2 (0.60) | KCNH2 | |
| SCHEMBL1266668 | 0.80 | KCNH2 (0.60) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8012961-B2 | Tricyclic antibiotics | ACTELION PHARMACEUTICAL LTD. (CH) | 2011-09-06 | — | — | US | disclosed |