Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 2/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.31 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.31 |
| ▸ | NEK1 | Q96PY6 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8764230 | 0.87 | MEN1 (0.64) | MEN1KMT2AMMP9MMP13NR1H2 | |
| SCHEMBL2023212 | 0.81 | MEN1 (0.52) | MEN1KMT2ATAAR1 | |
| SCHEMBL9553366 | 0.80 | MEN1 (0.47) | MEN1KMT2AMMP9MMP13NR1H2 | |
| SCHEMBL9552869 | 0.80 | KMT2A (0.56) | MEN1KMT2AMMP9MMP13NR1H2 | |
| SCHEMBL8763175 | 0.80 | MEN1 (0.56) | MEN1KMT2AMMP9MMP13NR1H2 | |
| SCHEMBL9553611 | 0.77 | MEN1 (0.44) | MEN1KMT2AMMP9MMP13NR1H2 | |
| SCHEMBL450038 | 0.76 | ESR1 (0.59) | MEN1KMT2AALDH1A1TDP1CYP1A2 | |
| SCHEMBL5690474 | 0.76 | MEN1 (0.52) | MEN1KMT2AMMP9MMP13NR1H2 | |
| SCHEMBL9788917 | 0.76 | MEN1 (0.52) | MEN1KMT2AMMP9MMP13ALDH1A1 | |
| SCHEMBL1066422 | 0.76 | MEN1 (0.52) | MEN1KMT2AALDH1A1KCNH2TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4006033-A1 | ADENOSINE RECEPTOR ANTAGONIST | Xiamen Biotime Biotechnology Co., Ltd. (CN) | 2022-06-01 | — | — | EP | disclosed |