Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 0.66 |
| ▸ | DPP8 | Q6V1X1 | 17/20 | 0.61 |
| ▸ | DPP9 | Q86TI2 | 16/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 10/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2702776 | 0.79 | DPP4 (1.00) | DPP4DPP8DPP9CYP3A4CYP2C19 | |
| SCHEMBL2703708 | 0.78 | DPP4 (1.00) | DPP4DPP8DPP9CYP3A4CYP2C19 | |
| SCHEMBL2703328 | 0.76 | DPP4 (1.00) | DPP4DPP8DPP9CYP3A4CYP2C19 | |
| SCHEMBL2703543 | 0.74 | DPP4 (1.00) | DPP4DPP8DPP9CYP3A4CYP2C19 | |
| SCHEMBL2703097 | 0.74 | DPP4 (1.00) | DPP4DPP8DPP9CYP3A4CYP2C19 | |
| SCHEMBL2703408 | 0.74 | DPP4 (1.00) | DPP4DPP8DPP9CYP3A4CYP2C19 | |
| SCHEMBL2702806 | 0.74 | DPP4 (1.00) | DPP4DPP8DPP9CYP3A4CYP2C19 | |
| SCHEMBL2704351 | 0.74 | DPP4 (1.00) | DPP4DPP8DPP9CYP3A4CYP2C19 | |
| SCHEMBL2702861 | 0.74 | DPP4 (1.00) | DPP4DPP8DPP9CYP3A4CYP2C19 | |
| SCHEMBL2704246 | 0.73 | DPP4 (1.00) | DPP4DPP8DPP9CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4005638-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2022-06-01 | — | — | EP | disclosed |