Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITK | Q08881 | 12/20 | 0.83 |
| ▸ | BTK | Q06187 | 15/20 | 0.83 |
| ▸ | JAK3 | P52333 | 14/20 | 0.83 |
| ▸ | TXK | P42681 | 13/20 | 0.83 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14460867 | 0.97 | ITK (0.87) | ITKBTKJAK3TXK | |
| SCHEMBL24467257 | 0.91 | BTK (0.82) | ITKBTKJAK3TXK | |
| SCHEMBL20162007 | 0.91 | ITK (1.00) | ITKBTKJAK3TXK | |
| SCHEMBL20161488 | 0.91 | BTK (1.00) | ITKBTKJAK3TXK | |
| SCHEMBL20161688 | 0.91 | BTK (1.00) | ITKBTKJAK3TXK | |
| SCHEMBL14460675 | 0.90 | ITK (1.00) | ITKBTKJAK3TXK | |
| SCHEMBL24467279 | 0.89 | ITK (0.83) | ITKBTKJAK3TXK | |
| SCHEMBL14461103 | 0.88 | ITK (0.83) | ITKBTKJAK3TXK | |
| SCHEMBL20161227 | 0.88 | JAK3 (1.00) | ITKBTKJAK3TXK | |
| SCHEMBL14460868 | 0.88 | ITK (1.00) | ITKBTKJAK3TXK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3534899-B1 | COMPOUNDS AND METHODS FOR MODULATING INTERLEUKIN-2-INDUCIBLE T-CELL KINASE | CORVUS PHARMACEUTICALS INC (US) | 2022-06-01 | — | — | EP | disclosed |
| US-9593073-B2 | Method for the preparation of diazoalkanes | BAKHU LIMITED (GB) | 2017-03-14 | — | — | US | disclosed |