Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TXK | P42681 | 19/20 | 1.00 |
| ▸ | ITK | Q08881 | 12/20 | 1.00 |
| ▸ | BTK | Q06187 | 11/20 | 1.00 |
| ▸ | JAK3 | P52333 | 13/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20161872 | 1.00 | TXK (1.00) | TXKITKBTKJAK3 | |
| SCHEMBL24467254 | 0.92 | TXK (1.00) | TXKITKBTKJAK3 | |
| SCHEMBL20161542 | 0.92 | TXK (1.00) | TXKITKBTKJAK3 | |
| SCHEMBL20161443 | 0.85 | TXK (1.00) | TXKITKBTKJAK3 | |
| SCHEMBL24467272 | 0.85 | TXK (1.00) | TXKITKBTKJAK3 | |
| SCHEMBL24467219 | 0.81 | TXK (1.00) | TXKITKBTKJAK3 | |
| SCHEMBL20161865 | 0.81 | TXK (1.00) | TXKITKBTKJAK3 | |
| SCHEMBL20161468 | 0.81 | TXK (1.00) | TXKITKBTKJAK3 | |
| SCHEMBL24467280 | 0.81 | TXK (1.00) | TXKITKBTKJAK3 | |
| SCHEMBL23366042 | 0.81 | TXK (1.00) | TXKITKBTKJAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3534899-B1 | COMPOUNDS AND METHODS FOR MODULATING INTERLEUKIN-2-INDUCIBLE T-CELL KINASE | CORVUS PHARMACEUTICALS INC (US) | 2022-06-01 | — | — | EP | disclosed |