Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TXK | P42681 | 15/20 | 1.00 |
| ▸ | JAK3 | P52333 | 15/20 | 1.00 |
| ▸ | BTK | Q06187 | 15/20 | 1.00 |
| ▸ | ITK | Q08881 | 8/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20161502 | 1.00 | TXK (1.00) | TXKJAK3BTKITK | |
| SCHEMBL20161214 | 0.91 | JAK3 (1.00) | TXKJAK3BTKITK | |
| SCHEMBL20161891 | 0.91 | JAK3 (1.00) | TXKJAK3BTKITK | |
| SCHEMBL24467325 | 0.88 | TXK (0.84) | TXKJAK3BTKITK | |
| SCHEMBL23365931 | 0.87 | BTK (0.77) | TXKJAK3BTKITK | |
| SCHEMBL24467300 | 0.86 | JAK3 (1.00) | TXKJAK3BTKITK | |
| Soquelitinib SCHEMBL20161402 | 0.86 | TXK (1.00) | TXKJAK3BTKITK | |
| Soquelitinib SCHEMBL20161546 | 0.86 | TXK (1.00) | TXKJAK3BTKITK | |
| Soquelitinib SCHEMBL24467290 | 0.86 | TXK (1.00) | TXKJAK3BTKITK | |
| SCHEMBL20161678 | 0.86 | JAK3 (1.00) | TXKJAK3BTKITK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3534899-B1 | COMPOUNDS AND METHODS FOR MODULATING INTERLEUKIN-2-INDUCIBLE T-CELL KINASE | CORVUS PHARMACEUTICALS INC (US) | 2022-06-01 | — | — | EP | disclosed |