Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 15/20 | 0.82 |
| ▸ | BTK | Q06187 | 12/20 | 0.68 |
| ▸ | TXK | P42681 | 10/20 | 0.66 |
| ▸ | ITK | Q08881 | 4/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24467326 | 0.90 | JAK3 (1.00) | JAK3BTKTXK | |
| SCHEMBL20161230 | 0.90 | JAK3 (1.00) | JAK3BTKTXK | |
| SCHEMBL27089719 | 0.90 | JAK3 (0.90) | JAK3BTKTXK | |
| SCHEMBL23366098 | 0.90 | JAK3 (0.84) | JAK3BTKTXKITK | |
| SCHEMBL23366088 | 0.88 | JAK3 (0.95) | JAK3BTKTXKITK | |
| SCHEMBL20161885 | 0.87 | JAK3 (1.00) | JAK3BTKTXK | |
| SCHEMBL23366099 | 0.87 | JAK3 (1.00) | JAK3BTKTXK | |
| SCHEMBL24467223 | 0.87 | JAK3 (1.00) | JAK3BTKTXK | |
| SCHEMBL27089716 | 0.87 | JAK3 (0.89) | JAK3BTKTXK | |
| SCHEMBL23365956 | 0.85 | JAK3 (0.95) | JAK3BTKTXKITK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3534899-B1 | COMPOUNDS AND METHODS FOR MODULATING INTERLEUKIN-2-INDUCIBLE T-CELL KINASE | CORVUS PHARMACEUTICALS INC (US) | 2022-06-01 | — | — | EP | disclosed |