Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 20/20 | 0.69 |
| ▸ | KDR | P35968 | 19/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25858431 | 0.86 | RET (0.70) | RETKDR | |
| SCHEMBL25858443 | 0.84 | RET (0.70) | RETKDR | |
| SCHEMBL24744024 | 0.84 | RET (0.72) | RETKDR | |
| SCHEMBL25858381 | 0.83 | RET (0.69) | RETKDR | |
| SCHEMBL24467467 | 0.83 | RET (0.70) | RETKDR | |
| SCHEMBL25858524 | 0.83 | RET (0.69) | RETKDR | |
| SCHEMBL25858507 | 0.83 | RET (0.69) | RETKDR | |
| SCHEMBL25858477 | 0.83 | RET (0.70) | RETKDR | |
| SCHEMBL25858435 | 0.83 | RET (0.69) | RETKDR | |
| SCHEMBL25858394 | 0.83 | RET (0.69) | RETKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3609898-B1 | COMPOUNDS USEFUL AS RET INHIBITORS | CANCER RESEARCH TECH LTD (GB) | 2022-06-01 | — | — | EP | disclosed |