Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 14/20 | 0.42 |
| ▸ | HCRTR2 | O43614 | 10/20 | 0.42 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.33 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.32 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.32 |
| ▸ | MLNR | O43193 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | BCL2 | P10415 | 1/20 | 0.31 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2447698 | 0.94 | HCRTR1 (0.44) | HCRTR1HCRTR2 | |
| SCHEMBL2442934 | 0.94 | HCRTR1 (0.45) | HCRTR1HCRTR2 | |
| SCHEMBL2450783 | 0.94 | HCRTR1 (0.42) | HCRTR1HCRTR2 | |
| SCHEMBL3413228 | 0.90 | HCRTR1 (0.48) | HCRTR1HCRTR2 | |
| SCHEMBL2445397 | 0.90 | HCRTR1 (0.50) | HCRTR1HCRTR2 | |
| SCHEMBL3413357 | 0.88 | HCRTR1 (0.47) | HCRTR1HCRTR2 | |
| SCHEMBL496035 | 0.88 | HCRTR1 (0.54) | HCRTR1HCRTR2NR1I3 | |
| SCHEMBL2447219 | 0.88 | HCRTR1 (0.43) | HCRTR1HCRTR2 | |
| SCHEMBL3414530 | 0.87 | HCRTR1 (0.45) | HCRTR1HCRTR2 | |
| SCHEMBL3415509 | 0.85 | HCRTR1 (0.54) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2164847-B1 | 3-AZA-BICYCLO[3.3.0]OCTANE COMPOUNDS | ACTELION PHARMACEUTICALS LTD (CH) | 2011-09-14 | — | — | EP | claimed |