Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UGCG | Q16739 | 12/20 | 0.59 |
| ▸ | NR1I2 | O75469 | 9/20 | 0.56 |
| ▸ | PARP2 | Q9UGN5 | 4/20 | 0.34 |
| ▸ | PARP1 | P09874 | 3/20 | 0.34 |
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24469605 | 1.00 | UGCG (0.59) | UGCGNR1I2PARP2PARP1DPP4 | |
| SCHEMBL30830107 | 0.85 | UGCG (0.61) | UGCGNR1I2PARP2PARP1DPP4 | |
| SCHEMBL29606253 | 0.85 | UGCG (0.61) | UGCGNR1I2PARP2PARP1 | |
| SCHEMBL29606133 | 0.85 | UGCG (0.61) | UGCGNR1I2PARP2PARP1DPP4 | |
| SCHEMBL29606499 | 0.85 | UGCG (0.61) | UGCGNR1I2PARP2PARP1 | |
| SCHEMBL24469465 | 0.85 | UGCG (0.61) | UGCGNR1I2PARP2PARP1 | |
| SCHEMBL24469664 | 0.85 | UGCG (0.61) | UGCGNR1I2PARP2PARP1 | |
| SCHEMBL24469532 | 0.84 | UGCG (0.67) | UGCGNR1I2 | |
| SCHEMBL24469537 | 0.84 | UGCG (0.67) | UGCGNR1I2 | |
| SCHEMBL29606305 | 0.84 | UGCG (0.60) | UGCGNR1I2PARP2PARP1DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022115301-A1 | MODIFIED ISOINDOLINONES AS GLUCOSYLCERAMIDE SYNTHASE INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2022-06-02 | — | — | WO | disclosed |