SCHEMBL24473534

SCHEMBL24473534

CC1(C(=O)N[C@@H](Cc2ccc(Br)cc2)C(=O)N[C@@H](CC2CCCC2)C(=O)O)CCC/C=C\CC(N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N1

nearest known ligand 0.53

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
NTSR2 O95665 8/20 0.53
PRKAR2A P13861 8/20 0.46
PRKAR2B P31323 6/20 0.46
EIF4E P06730 2/20 0.43
EIF4EBP1 Q13541 2/20 0.43
ACE2 Q9BYF1 1/20 0.41
NTSR1 P30989 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24473416 0.94 NTSR2 (0.60) NTSR2PRKAR2APRKAR2BEIF4EEIF4EBP1
SCHEMBL24473444 0.92 NTSR2 (0.46) NTSR2PRKAR2APRKAR2BEIF4EEIF4EBP1
SCHEMBL24473579 0.86 NTSR2 (0.53) NTSR2PRKAR2APRKAR2BEIF4EEIF4EBP1
SCHEMBL24473339 0.85 NTSR2 (0.73) NTSR2PRKAR2APRKAR2BEIF4EEIF4EBP1
SCHEMBL24473505 0.85 NTSR2 (0.73) NTSR2PRKAR2APRKAR2BEIF4EEIF4EBP1
SCHEMBL24473602 0.81 NTSR2 (0.71) NTSR2PRKAR2APRKAR2BEIF4EEIF4EBP1
SCHEMBL24473637 0.81 NTSR2 (0.61) NTSR2PRKAR2APRKAR2BEIF4EEIF4EBP1
SCHEMBL24473489 0.79 NTSR2 (0.79) NTSR2NTSR1
SCHEMBL24473501 0.79 NTSR2 (0.78) NTSR2NTSR1
SCHEMBL24473385 0.79 NTSR2 (0.78) NTSR2NTSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220168383-A1 NEUROTENSINERGIC AGONISTS AND METHODS OF USING SAME PREVENTING OR TREATING PAIN SOCPRA SCIENCES SANTÉ ET HUMAINES S.E.C. (CA) 2022-06-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220168383-A1 NEUROTENSINERGIC AGONISTS AND METHODS OF USING SAME PREVENTING OR TREATING PAIN VIP, NTSR2, VIPR2 NTSR2 2/4885PRKAR2A 419/4885PRKAR2B 537/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.